This test is done to evaluate whether your body may have difficulty breaking down histamine due to low activity of the enzyme diamine oxidase (DAO). When DAO levels are reduced, histamine can accumulate in the body and may contribute to symptoms such as headaches, skin flushing, hives, or digestive discomfort, especially after eating certain foods. The test helps investigate whether histamine intolerance could be a possible explanation for these recurring symptoms.

• -If you experience repeated headaches, flushing, or skin reactions after meals
• -If you have digestive symptoms such as bloating, diarrhea, or abdominal discomfort without a clear cause
• -If symptoms worsen after consuming histamine-rich foods (e.g., aged cheese, wine, fermented foods)
• -When standard allergy and digestive tests have not identified the cause of symptoms

• -No specific preparation is usually required
• -Follow any instructions provided by the laboratory
• -Inform your healthcare provider about any medications or supplements you are taking, as some may influence histamine levels